Publications


 
 

2019

Neural Circuitry of Novelty Salience Processing in Psychosis Risk: Association with Clinical Outcome

Modinos G, Allen PA, Zugman A, Dima D, Azis M, Samson C, Bonoldi I, Quinn B, Gifford GWG, Smart SE, Antoniades M, Bossong MG, Broome MR, Perez J, Howes OD, Stone JM, Grace AA, McGuire P.

Schizophr Bull. 2019 (in press).


Basic Self-Disturbances Related to Reduced Anterior Cingulate Volume in Subjects at Ultra-High Risk for Psychosis

Bonoldi I, Allen P, Madeira L, Tognin S, Bossong MG, Azis M, Samson C, Quinn B, Calem M, Valmaggia L, Modinos G, Stone J, Perez J, Howes O, Politi P, Kempton MJ, Fusar-Poli P, McGuire P.

Front Psychiatry. 2019 May 10;10:254.


Oxytocin modulates hippocampal perfusion in people at clinical high risk for psychosis

Davies C, Paloyelis Y, Rutigliano G, Cappucciati M, De Micheli A, Ramella-Cravaro V, Provenzani U, Antoniades M, Modinos G, Oliver D, Stahl D, Murguia S, Zelaya F, Allen, P, Shergill S, Morrison P, Williams S, Taylor D, McGuire P. & Fusar-Poli, P.

Neuropsychopharmacology. 2019 Jun;44(7):1300-1309.


Multi-echo fMRI, resting-state connectivity, and high psychometric schizotypy

Waltmann M, O'Daly O, Egerton A, McMullen K, Kumari V, Barker GJ, Williams SCR, Modinos G.

Neuroimage Clin. 2019;21:101603.


 

2018

Association of hippocampal glutamate levels with adverse outcomes in individuals at clinical high risk for psychosis

Bossong MG, Antoniades M, Azis M, Samson C, Quinn B, Bonoldi I, Modinos G, Perez J, Howes OD, Stone JM, Allen P, McGuire P.

JAMA Psychiatry. 2018 Nov 14. doi: 10.1001/jamapsychiatry.2018.3252. [Epub ahead of print]


Increased resting perfusion of the hippocampus in high positive schizotypy: A pseudocontinuous arterial spin labeling study

Modinos G, Egerton A, McMullen K, McLaughlin A, Kumari V, Barker GJ, Williams SCR, Zelaya F.

Hum Brain Mapp. 2018 Oct;39(10):4055-4064


Prefrontal GABA levels, hippocampal resting perfusion and the risk of psychosis

Modinos G, Şimşek F, Azis M, Bossong M, Bonoldi I, Samson C, Quinn B, Perez J, Broome MR, Zelaya F, Lythgoe DJ, Howes OD, Stone JM, Grace AA, Allen P, McGuire P.

Neuropsychopharmacology. 2018 Dec;43(13):2660


Cortical GABA in Subjects at Ultra-High Risk of Psychosis: Relationship to Negative Prodromal Symptoms

Modinos G, Şimşek F, Horder J, Bossong M, Bonoldi I, Azis M, Perez J, Broome M, Lythgoe DJ, Stone JM, Howes OD, Murphy DG, Grace AA, Allen P, McGuire P.

Int J Neuropsychopharmacol. 2018 Feb 1;21(2):114-119


Increased Resting Hippocampal and Basal Ganglia Perfusion in People at Ultra High Risk for Psychosis: Replication in a Second Cohort

Allen P, Azis M, Modinos G, Bossong MG, Bonoldi I, Samson C, Quinn B, Kempton MJ, Howes OD, Stone JM, Calem M, Perez J, Bhattacharayya S, Broome MR, Grace AA, Zelaya F, McGuire P.

Schizophr Bull. 2018 Oct 17;44(6):1323-1331


Neuroanatomical changes in people with high schizotypy: relationship to glutamate levels

Modinos G, Egerton A, McLaughlin A, McMullen K, Kumari V, Lythgoe DJ, Barker GJ, Aleman A, Williams SCR.

Psychol Med. 2018 Aug;48(11):1880-1889


 

2017

Phenomenology and Social Agent Representation in Psychosis: A Welcome Integration

Bell V, Mills KL, Modinos G, Wilkinson S.

Clin Psychol Sci. 2017 Sep;5(5):769-770.


Neuroimaging studies of GABA in schizophrenia: a systematic review with meta-analysis

Egerton A, Modinos G, Ferrera D, McGuire P.

Transl Psychiatry. 2017 Jun 6;7(6):e1147.


Rethinking Social Cognition in Light of Psychosis: Reciprocal Implications for Cognition and Psychopathology

Bell V, Mills KL, Modinos G, Wilkinson S.

Clin Psychol Sci. 2017 May;5(3):537-550.


Corticolimbic hyper-response to emotion and glutamatergic function in people with high schizotypy: a multimodal fMRI-MRS study

Modinos G, McLaughlin A, Egerton A, McMullen K, Kumari V, Barker GJ, Keysers C, Williams SC.

Transl Psychiatry. 2017 Apr 4;7(4):e1083


 

2016

Corticolimbic dysfunction during facial and prosodic emotional recognition in first-episode psychosis patients and individuals at ultra-high risk

Tseng HH, Roiser JP, Modinos G, Falkenberg I, Samson C, McGuire P, Allen P.

Neuroimage Clin. 2016 Sep 8;12:645-654.


 

2015

A systematic review of multisensory cognitive-affective integration in schizophrenia

Tseng HH, Bossong MG, Modinos G, Chen KM, McGuire P, Allen P.

Neurosci Biobehav Rev. 2015 Aug;55:444-52


Failure to deactivate medial prefrontal cortex in people at high risk for psychosis

Falkenberg I, Chaddock C, Murray RM, McDonald C, Modinos G, Bramon E, Walshe M, Broome M, McGuire P, Allen P.

Eur Psychiatry. 2015 Jul;30(5):633-40.


Neural correlates of aberrant emotional salience predict psychotic symptoms and global functioning in high-risk and first-episode psychosis

Modinos G, Tseng HH, Falkenberg I, Samson C, McGuire P, Allen P.

Soc Cogn Affect Neurosci. 2015 Oct;10(10):1429-36.


Translating the MAM model of psychosis to humans

Modinos G, Allen P, Grace AA, McGuire P.

Trends Neurosci. 2015 Mar;38(3):129-38.


The prodromal phase of psychosis

Modinos G, McGuire P.

Curr Opin Neurobiol. 2015 Feb;30:100-5


 

2014

Are we really mapping psychosis risk? Neuroanatomical signature of affective disorders in subjects at ultra high risk

Modinos G, Allen P, Frascarelli M, Tognin S, Valmaggia L, Xenaki L, Keedwell P, Broome M, Valli I, Woolley J, Stone JM, Mechelli A, Phillips ML, McGuire P, Fusar-Poli P.

Psychol Med. 2014 Dec;44(16):3491-501


Identifying gene-environment interactions in schizophrenia: contemporary challenges for integrated, large-scale investigations

European Network of National Networks studying Gene-Environment Interactions in Schizophrenia (EU-GEI).

Schizophr Bull. 2014 Jul;40(4):729-36


 

2013

Voxel-based gray and white matter morphometry correlates of hallucinations in schizophrenia: The superior temporal gyrus does not stand alone

van Tol MJ, van der Meer L, Bruggeman R, Modinos G, Knegtering H, Aleman A.

Neuroimage Clin. 2013 Dec 29;4:249-57


Molecular genetic gene-environment studies using candidate genes in schizophrenia: a systematic review.

Modinos G, Iyegbe C, Prata D, Rivera M, Kempton MJ, Valmaggia LR, Sham PC, van Os J, McGuire P.

Schizophr Res. 2013 Nov;150(2-3):356-65



Neuroanatomy of auditory verbal hallucinations in schizophrenia: a quantitative meta-analysis of voxel-based morphometry studies

Modinos G, Costafreda SG, van Tol MJ, McGuire PK, Aleman A, Allen P.

Cortex. 2013 Apr;49(4):1046-55


 

2012

Neuroimaging auditory hallucinations in schizophrenia: from neuroanatomy to neurochemistry and beyond

Allen P, Modinos G, Hubl D, Shields G, Cachia A, Jardri R, Thomas P, Woodward T, Shotbolt P, Plaze M, Hoffman R.

Schizophr Bull. 2012 Jun;38(4):695-703.


Multivariate pattern classification reveals differential brain activation during emotional processing in individuals with psychosis proneness

Modinos G, Pettersson-Yeo W, Allen P, McGuire PK, Aleman A, Mechelli A.

Neuroimage. 2012 Feb 1;59(3):3033-41


 

2011

Self-reflection and the psychosis-prone brain: an fMRI study

Modinos G, Renken R, Ormel J, Aleman A.

Neuropsychology. 2011 May;25(3):295-305


 

2010

The 2nd Schizophrenia International Research Society Conference, 10-14 April 2010, Florence, Italy: summaries of oral sessions

Baharnoori M, Bartholomeusz C, Boucher AA, Buchy L, Chaddock C, Chiliza B, Föcking M, Fornito A, Gallego JA, Hori H, Huf G, Jabbar GA, Kang SH, El Kissi Y, Merchán-Naranjo J, Modinos G, Abdel-Fadeel NA, Neubeck AK, Ng HP, Novak G, Owolabi OO, Prata DP, Rao NP, Riecansky I, Smith DC, Souza RP, Thienel R, Trotman HD, Uchida H, Woodberry KA, O'Shea A, DeLisi LE.

Schizophr Res. 2010 Dec;124(1-3):e1-62.


Neurobiological correlates of theory of mind in psychosis proneness

Modinos G, Renken R, Shamay-Tsoory SG, Ormel J, Aleman A.

Neuropsychologia. 2010 Nov;48(13):3715-24



Individual differences in dispositional mindfulness and brain activity involved in reappraisal of emotion

Modinos G, Ormel J, Aleman A.

Soc Cogn Affect Neurosci. 2010 Dec;5(4):369-77


Schizotypy and brain structure: a voxel-based morphometry study

Modinos G, Mechelli A, Ormel J, Groenewold NA, Aleman A, McGuire PK.

Psychol Med. 2010 Sep;40(9):1423-31.


 

2009

Structural covariance in the hallucinating brain: a voxel-based morphometry study

Modinos G, Vercammen A, Mechelli A, Knegtering H, McGuire PK, Aleman A.

J Psychiatry Neurosci. 2009 Nov;34(6):465-9.


Cortisol levels in childhood and psychosis risk in late adolescence

Modinos G, Aleman A, Ormel J.

J Am Acad Child Adolesc Psychiatry. 2009 Jul;48(7):765-6


Theory of Mind in different dementia profiles

Modinos G, Obiols JE, Pousa E, Vicens J.

J Neuropsychiatry Clin Neurosci. 2009 Winter;21(1):100-1.


Activation of anterior insula during self-reflection

Modinos G, Ormel J, Aleman A.

PLoS One. 2009;4(2):e4618


Detection of visuoperceptual deficits in preclinical and mild Alzheimer's disease

Alegret M, Boada-Rovira M, Vinyes-Junqué G, Valero S, Espinosa A, Hernández I, Modinos G, Rosende-Roca M, Mauleón A, Becker JT, Tárraga L.

J Clin Exp Neuropsychol. 2009 Oct;31(7):860-7


 

2006

A randomised pilot study to assess the efficacy of an interactive, multimedia tool of cognitive stimulation in Alzheimer's disease

Tárraga L, Boada M, Modinos G, Espinosa A, Diego S, Morera A, Guitart M, Balcells J, López OL, Becker JT.

J Neurol Neurosurg Psychiatry. 2006 Oct;77(10):1116-21.